Neutralization of human parvovirus B19 by plasma and intravenous immunoglobulins

Intrauterine anemia due to parvovirus B19: successful treatment with intravenous immunoglobulins.

air spaces and absence of hyperplastic pneumocytes (type II) with bizarre shapes usually noted in cases of bleomycin-induced interstitial pneumonitis.10 The pathologic changes described in our patient are different from those described for bleomycin hypersensitivity pneumonitis and appear to be a classic bleomycin intestitial pneumonitis.11 This case illustrates that life threatening bleomycin ...

miRNA and tropism of human parvovirus B19

Parvovirus B19 has an extreme tropism for human erythroid progenitors. Here we propose the hypothesis explaining the tropism of human parvovirus B19. Our speculations are based on experimental results related to the capsid proteins VP1 and VP2. These proteins were not detectable in nonpermissive cells in course of these experiments, although the corresponding mRNAs were synthesized. Our interpr...

Hereditary Spherocytosis Unmasked by Human Parvovirus B19 Induced Aplastic Crisis in a Family

Human parvovirus (HPV) B19 induced aplastic crisis in a family leading to the diagnosis of hereditary spherocytosis (HS) is a very rare condition being barely reported in the literature. We herein report a 4-year-old girl, her brother, and their mother who all presented with progressive pallor and jaundice after a febrile illness. The HPV B19 was diagnosed using polymerase chain reaction (PCR) ...

Human parvovirus B19 and pediatric rheumatologic disease

Purpose Human Parvovirus B19 causes a self-limited febrile illness with a characteristic exanthem and occasional acute arthritis. B19 infection has also been associated with multiple rheumatic diseases. Reports indicate that in patients with positive B19 PCR up to ~1/3 have negative IgM and positive IgG to B19. However little is known about how these findings might relate to rheumatologic sympt...

Henoch-Schönlein purpura and human parvovirus B19.